Is there any merit to flatting in this spot vs a good reg to keep in the very loose player on the button? I know that it is a standard 4-bet in theory, but pushing out the lag in order to flip against the pro doesn't seem like a great play.
PLO Trainer prefers x/calling over leading. Check/raising is tricky, as the solver sometimes checks/raises these combos, but FOLDS vs flop 3-Bet. This can be expensive if your opponent is 3-betting flop too light. So I would lean towards check/calling, or leading.