Weaponizing Caffeine for Strength & Performance
What it is: Caffeine is a natural central nervous system stimulant found in coffee, tea, cacao, and synthesized for supplements (e.g., caffeine anhydrous). It’s the most researched and widely used ergogenic aid in performance.¹ How it works: 1. Adenosine receptor antagonist – blocks adenosine to reduce fatigue and increase alertness.² 2. Increases catecholamines (epinephrine, norepinephrine) – elevates heart rate, focus, reaction time, and energy output.³ 3. Mobilizes fatty acids – can spare glycogen in endurance tasks.⁴ 4.Improves neuromuscular function – enhances motor unit recruitment, power, and perceived effort tolerance.⁵ Performance effects: ↑ endurance capacity ↑ strength & power output ↑ reaction time & vigilance ↓ perceived exertion (RPE)¹˒⁵ When to use it for performance: 1. Take 30–60 minutes pre-training/event (peak plasma concentration window).² 2. Dose: 2–3 mg/kg is effective; 3–6 mg/kg is upper performance range. Higher offers minimal added benefit and increases side effects.¹˒⁵ 3. Example: 90 kg (200 lb) athlete → 180–270 mg (2–3 mg/kg) ideal start. Best use cases: 1. High-intensity training 2. Strength/power sessions 3. Endurance events 4. Sleep-restricted or extended operations Avoid/limit if: 1. Late-day use that impacts sleep (half-life 4–6 hrs).² 2. You’re caffeine sensitive (jitters, anxiety, GI distress, elevated HR/BP).¹ Bottom line: Caffeine sharpens the brain, boosts output, lowers fatigue, and improves performance when dosed properly and timed with intent. Use it strategically, not habitually. References 1. Grgic J, et al. J Int Soc Sports Nutr. 2020;17:2. 2. Nehlig A. Neurosci Biobehav Rev. 2010;34(2):285-301. 3. Davis JM, et al. Med Sci Sports Exerc. 2003;35(8):1361-6. 4. Spriet LL. Appl Physiol Nutr Metab. 2014;39(11):1310-28. 5. Guest NS, et al. J Int Soc Sports Nutr. 2021;18:1.