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1 contribution to Research Peptide Community
Switching glp2-glp3 advice
My cousin and I were looking into R-GLP3. We're currently involved with T-GLP2. Anyone who's been here, can you please give as much detail as possible? Because when you switch do you start back at the bottom? Up by 2.5 and such? I heard it helps tremendously with inflammation. Experiences with research you've done on it?
3 likes • Dec '25
Good luck with GLP-3. It is way more potent than GLP-2 so it is not in the same scale (ie, 2.5 mg increments). Start with 1 mg/week. Similar side effects to GLP-2. Nausea, GI, - but also some new side effects reported - 8-10 bpm increase in pulse, sleep disruption, “sunburn” type skin sensitivity. Also, compared to Tirz, Reta does not have as strong of a food noise reduction- so you may find a resumption of that. Titrate up slowly- give yourself at least a few weeks at each level to monitor side effects. More is not better. Max benefits in Phase 2 was at 8 mg/week. Phase 3 results that were just published showed max benefits at 12 mg/week.
2 likes • 28d
@Kendall Gaines so the amount of a peptide is measured in mg. When you buy a vial of peptide it comes in 5 mg, 10 mg, 50 mg, etc. This is a measure of WEIGHT of the powder in the vial. Units measures the VOLUME of liquid in a syringe after it’s been reconstituted. On a U-100 syringe, a unit is 1/100 of a mL. Depending on how much solution was used to reconstitute the peptide in the vial, a “unit” could vary in how much peptide it contains. So think about a unit as the amount of peptide (mg) divided by the volume of solution (in mL). So if you take a 10 mg vial and reconstitute it with 1 mL of BAC water, then 10 units has 1 mg of peptide. If you take that same vial of 10 mg but chose to reconstitute it instead with 2 mL of BAC water then the same 10 units would only have half the peptide, or 0.5 mg. This is why talking about units is not helpful to understanding how much peptide you are dosing. Dosages should always be given in terms of mg (weight) not units (volume) since you always need to understand how much solution was used to reconstitute so you can measure the concentration in solution properly. Does that help?
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Barry Freeman
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@barry-freeman-5769
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