Okay, I've talked about split dosing in the past, but let's talk about it specifically for GLP-1s and get some community feedback here. Plus, we have a lot of new researchers in here that probably haven't been introduced to this concept, so it's worth bringing up again. Here's something that surprises a lot of people: the once-a-week dosing schedule for GLP-1s like semaglutide and tirzepatide wasn't designed to give you the best results. It was designed so the most people would actually stick with it. And there's a big difference. Let me break this down in the simplest way possible. First, What's a Half-Life? (The 60-Second Version) Think of a half-life like an hourglass. When you administer a peptide, the hourglass flips. The half-life is how long it takes for half of that peptide to leave your system. - Semaglutide has a half-life of roughly 5-7 days (≈160-168 hours) - Tirzepatide has a half-life of roughly 5 days (≈120 hours) - Retatrutide has a half-life of roughly 6 days (≈144 hours) So if you administer semaglutide on Monday, by the following Sunday, about half of it is still working. Sounds great, right? Well... sort of. Why Once a Week Creates a Roller Coaster Here's a common misconception: your levels don't spike on administration day. GLP-1 concentration actually takes time to build up in your system after each dose. But once those levels peak, they start to fall off over the course of seven days. And here's the bigger picture — it actually takes about four weeks of consistent dosing for the peptide to fully build up in your system and reach true steady-state titration. That's why the effects feel different in week one versus week four at the same dose. But even after you've reached steady state, the once-weekly pattern still creates a wave within each week: - After administration, Levels gradually rise over the first couple of days as the peptide absorbs and builds. - Mid-week: You hit your peak concentration. This is when effects are strongest — but also when side effects like nausea can be most noticeable. - Days 5-7: Levels are declining. This is when many people report the appetite suppression "wearing off," food noise creeping back in, and increased cravings toward the end of the week.

Good morning and happy Presidents Day, everybody! Just finished a full pricing update across the board on peptideprice.store — all retailers are current as of this morning. I'll attach a graph of some of the prices that have been changing across the board so you can get an idea of what this is going to look like with price tracking. I think this will be a very useful feature over time! We've also got a new logo! With price tracking now live, it felt like the perfect time for a fresh look. Let me know what you think down below 👇 And we're kicking off the week with a new series: peptides that help the most after 40. First post is coming soon — stay tuned. As always, check out all the latest sales here: 🔗 peptideprice.store/sales Have a great Monday!

If you're over 40 and you haven't looked into growth hormone secretagogues yet — this is where I'd start. Before anything else. Before fat loss peptides, before recovery peptides, before anything. All content is for research and educational purposes only, not medical advice! Here's why. In my opinion, the single most important thing you lose as you start to age is recovery. Everything slows down. Your joints ache longer. Your muscles take days to bounce back instead of hours. That nagging shoulder that used to heal in a week? Now it lingers for months. Cuts heal slower. Sleep gets worse. You just don't bounce back like you used to. And the root cause behind a LOT of that? Your IGF-1 levels are naturally declining. IGF-1 (Insulin-like Growth Factor 1) is the downstream marker of growth hormone. It's the thing that actually drives tissue repair, fat metabolism, muscle maintenance, collagen production, and recovery at the cellular level. And it drops off a cliff as you age — because your growth hormone drops off a cliff as you age. Growth hormone declines approximately 14% every decade after your mid-30s. By the time you're 50-60, you're producing a fraction of what you did at your peak. That decline has a medical name — somatopause — and it's responsible for basically the entire checklist of things we blame on "getting old": • Gaining fat (especially around the midsection) despite not eating more • Losing muscle despite still training • Recovery taking forever • Sleep quality tanking — especially deep sleep • Skin getting thinner, more wrinkles • Brain fog, less mental sharpness • Weaker immune function • Less energy across the board Sound familiar? That's not just "aging." That's declining growth hormone and IGF-1. So if you're 40+ and looking for the FIRST thing to optimize — this is it. Get your IGF-1 levels tested. Know your baseline. And then let's talk about the tools that can help. That's what growth hormone secretagogues are. And that's what this post is about.

🚨 Two Valentine’s Day Sales Extended Through Tuesday, Feb 17th Both AMP and EZ Peptides have been extended for President’s Day. If you’ve been on the fence, you’ve got a couple more days. Here’s what’s still live 👇 💘 AMP Peptides — Up to 35% Off + BOGO Topicals • 20% off sitewide (automatic) • Stack code DEREK15 for an extra 15% → 35% off total • ALL cosmetic/topical products are Buy One Get One FREE BOGO Topicals: CopperGlow Cream • Peptide Cream • Peptide Eye Cream • Resveratrol Booster Serum • Retinal X Serum • Sponge Microneedle Cream • Sponge Microneedle Scalp Serum 🔗 https://ameanopeptides.com/?ref=Derek15 🏷️ Code: DEREK15 🚚 Free shipping on orders over $200 📅 Ends Feb 17th 💘 EZ Peptides — Up to 30% Off + Giveaway • 30% off all singles • 25% off all kits • Use code DEREK at checkout GIVEAWAY — Build Your Own Variety Kit Leave a review at peptideprice.store/reviews and you’re entered to win a completely custom kit from EZ Peptides. 3 winners will be selected — you pick one GLP of your choice and fill the rest with whatever you want (multiples included). Since the sale is extended, we’ll be picking giveaway winners on February 18th — so you’ve got extra time to get your reviews in. 👉 https://ezpeptides.com/ref/derekliftz/ 📅 Ends Feb 17th —————————————— 🛠️ Modified Aminos — Coupon Fix Saw some of you having trouble stacking LAUNCH + DEREK at checkout. I talked to them and got it fixed — LAUNCH is now auto-applied, so all you need to enter is code DEREK for 30% off. Simple. 🔗 https://modifiedaminos.shop/?ref=derek —————————————— 🌟 New Company Joining the Price Tool This Week We’ve got a new vendor being added to peptideprice.store this week. Raising the bar as always — net purity, net content, endotoxins, and conformity. I’ll keep you guys updated as they go live.

Hey everyone! 👋 We're switching things up with the content going forward, and I want your input on this. The new game plan is to cover categories of peptides week by week — going deep on each one so we can build up a full catalog of knowledge and research for the community. I'm talking about covering everything we can possibly think of within each category so nothing gets left on the table. We already have courses on GLP-1s, GH secretagogues, muscle building, and more — but if we need to go back through any of those and expand on them, we absolutely will. This is about making sure we're covering what's most important to YOU and the research community as a whole. Nothing's going to change on the Q&A side — whenever you guys have questions or are curious about something you can't find, make a post or drop a comment. I'm also going to be doing a weekly Q&A thread so we have a dedicated space for that. So here's what I need from you — drop your answers down below: 👇 Which categories of peptides do you want to see covered first? 👇 Any specific topics within those categories you want us to dive into? 👇 Are there any existing courses you'd like us to revisit and build on? Your input is what shapes this. Let's build this thing together. 💪