Research Idea · Rishab Academy

Research Idea

can anyone tell me if my research idea is good / has high impact and is feasible???

Using a Machine Learning Pipeline trained on docking data along with vitro validation for the Computational and Experimental Optimization of Drug Candidates Targeting GABA Receptor Dysregulation in Epilepsy Treatment

RQ: How do different drug candidates impact the inhibition of GABA receptors to help fix temporal lobe epilepsy?

IV = Drug candidates (different GABA receptor inhibitors)

DV = GABA receptor activity (inhibition) -> GABA receptor must inhibit + activated in order to prevent epilepsy electrical signals

Basically i am using molecular docking + ML algorithms to optimize drug candidates to help activate gaba inhibitors (basically find a way to help cure temporal lobe epilepsy (which depends on gaba inhibitors). Current drugs all have side effects so i am trying to optimize

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