The Gut–Mood Connection You Should Know About
Recent research shows that irritation in the gut can send signals to the brain and change your mood (Hopkins Medicine, 2025).
A study published in Nature (2025) found that people with depression had lower gut bacterial diversity and higher levels of bacteria linked to inflammation — suggesting a connection between gut imbalance and depressive symptoms.
Researchers at Stanford Medicine (2025) also explained that communication between the gut and the brain — through the vagus nerve and chemical substances produced by gut bacteria — can affect conditions such as anxiety, long COVID, and Parkinson’s disease.
These studies show that keeping your gut healthy is essential for your emotional and mental well-being.
How do gut bacteria influence mood and brain function?
They produce vitamins that directly increase brain activity
They release neurotransmitters and inflammatory molecules that affect brain signaling through the vagus nerve
They change blood sugar levels, which alters brain temperature
They block the communication between neurons in the brain
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Priscila Stagliorio
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The Gut–Mood Connection You Should Know About
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