Question: Which feature is most characteristic of Corynebacterium diphtheriae?
β
Correct Answer: B) Metachromatic granules
π Shoutout to the member who voted and got it right! π
π§ Explanation:
One of the classic identifying features of Corynebacterium diphtheriae is the presence of metachromatic (Babes-Ernst) granules.
These granules are intracellular phosphate storage granules that can be visualized with special stains such as:
π¬ Albert stain
π¬ Methylene blue stain
High-Yield Clues for
C. diphtheriae
β Gram-positive rod
β Club-shaped appearance
β βChinese lettersβ or palisading arrangement
β Metachromatic granules
β Produces diphtheria toxin
β Why not the other options?
A) Beta-hemolysis on blood agar
β’ Not a defining characteristic of C. diphtheriae
C) Lactose fermentation
β’ More commonly used when identifying Gram-negative enteric organisms
D) Oxidase positivity
β’ Not a key identifying feature of C. diphtheriae
π‘ Quick Recall Tip
π Corynebacterium = Club-shaped rods + Chinese letters + Metachromatic granules
If you see those granules on an exam question, Corynebacterium diphtheriae should immediately come to mind!
π Did you get it right before seeing the answer?
Drop a π§« below!