What's a great Email Client that can be uses as a Unibox? (not Outlook)

I run several campaigns on different CRMs, and not all of them have the unibox and unibox reply features. So to easily access the replies, I'm thinking of connecting them all up to a single email client. I am currently using Outlook for my personal and business emails, not cold campaigns. Is there another client I can run on a Mac besides Outlook, each with its own configuration? Outlook has a unibox called "All.". So something similar would work.

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